Description: Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Santiago Grisolia, Vicente Felipo Format: Paperback Publisher: Springer-Verlag New York Inc., United States Imprint: Springer-Verlag New York Inc. ISBN-13: 9781461360582, 978-1461360582 Synopsis This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye's syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues, including brain, is also presented, as well as the effects of hyperammonemia on brain metabolism and function and on brain microtubules. The control of cerebral protein breakdown is reviewed. The classical and some recently proposed clinical treatments as well as nutritional considerations in the management of patients with liver failure are also discussed.
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Location: Aldershot
End Time: 2025-01-30T11:42:53.000Z
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Book Title: Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy
Number of Pages: 148 Pages
Publication Name: Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy
Language: English
Publisher: Springer-Verlag New York Inc.
Item Height: 254 mm
Subject: Medicine, Zoology, Biology
Publication Year: 2012
Type: Textbook
Item Weight: 316 g
Author: Vicente Felipo, Santiago Grisolia
Item Width: 178 mm
Series: Advances in Experimental Medicine and Biology
Format: Paperback
