Guide to Clinical and Diagnostic Virology by Reeti Khare (English) Hardcover Boo

Description: FREE SHIPPING UK WIDE Guide to Clinical and Diagnostic Virology by Reeti Khare The explosion in clinical testing has been especially rapid in virology, where emerging viruses and growing numbers of viral infections are driving advances. The Guide to Clinical and Diagnostic Virology offers a digestible view of the breadth and depth of information related to clinical virology, providing a practical, working knowledge of the wide array of viruses that cause human disease.Introductory chapters cover the basics of clinical virology and laboratory diagnosis of infections, including virus structure, life cycle, transmission, taxonomy, specimen types and handling, and a comparison of assays used for detection. Detailed sections on important topics includeViral pathogens and their clinical presentationsDiagnostic assays and techniques, including culture-based, immunological, and molecularPrevention and management of viral infections, with guidance on biosafety, vaccines, and antiviral therapiesThe regulatory environment for laboratory testing, including regulatory requirements and assay performance and interpretationCritical concepts are carefully curated and concisely summarized and presented with detailed illustrations that aid comprehension, along with important highlights and helpful hints. These features, plus question sections that reinforce significant ideas and key concepts, make this an invaluable text for anyone looking for an accessible route through clinical and diagnostic virology. Laboratory technologists, medical students, infectious disease and microbiology fellows, pathology residents, researchers, and everyone involved with viruses in the clinical setting will find the Guide to Clinical and Diagnostic Virology an excellent text as well as companion to clinical virology references. FORMAT Hardcover LANGUAGE English CONDITION Brand New Back Cover Guide to Clinical and Diagnostic Virology First Edition The explosion in clinical testing has been especially rapid in virology, where emerging viruses and growing numbers of viral infections are driving advances. The Guide to Clinical and Diagnostic Virology offers a digestible view of the breadth and depth of information related to clinical virology, providing a practical, working knowledge of the wide array of viruses that cause human disease. Introductory chapters cover the basics of clinical virology and laboratory diagnosis of infections, including virus structure, life cycle, transmission, taxonomy, specimen types and handling, and a comparison of assays used for detection. Detailed sections on important topics include Viral pathogens and their clinical presentations Diagnostic assays and techniques, including culture-based, immunological, and molecular Prevention and management of viral infections, with guidance on biosafety, vaccines, and antiviral therapies The regulatory environment for laboratory testing, including regulatory requirements and assay performance and interpretation Critical concepts are carefully curated and concisely summarized and presented with detailed illustrations that aid comprehension, along with important highlights and helpful hints. These features, plus question sections that reinforce significant ideas and key concepts, make this an invaluable text for anyone looking for an accessible route through clinical and diagnostic virology. Laboratory technologists, medical students, infectious disease and microbiology fellows, pathology residents, researchers, and everyone involved with viruses in the clinical setting will find the Guide to Clinical and Diagnostic Virology an excellent text as well as companion to clinical virology references. Flap Guide to Clinical and Diagnostic Virology First Edition The explosion in clinical testing has been especially rapid in virology, where emerging viruses and growing numbers of viral infections are driving advances. The Guide to Clinical and Diagnostic Virology offers a digestible view of the breadth and depth of information related to clinical virology, providing a practical, working knowledge of the wide array of viruses that cause human disease. Introductory chapters cover the basics of clinical virology and laboratory diagnosis of infections, including virus structure, life cycle, transmission, taxonomy, specimen types and handling, and a comparison of assays used for detection. Detailed sections on important topics include Viral pathogens and their clinical presentations Diagnostic assays and techniques, including culture-based, immunological, and molecular Prevention and management of viral infections, with guidance on biosafety, vaccines, and antiviral therapies The regulatory environment for laboratory testing, including regulatory requirements and assay performance and interpretation Critical concepts are carefully curated and concisely summarized and presented with detailed illustrations that aid comprehension, along with important highlights and helpful hints. These features, plus question sections that reinforce significant ideas and key concepts, make this an invaluable text for anyone looking for an accessible route through clinical and diagnostic virology. Laboratory technologists, medical students, infectious disease and microbiology fellows, pathology residents, researchers, and everyone involved with viruses in the clinical setting will find the Guide to Clinical and Diagnostic Virology an excellent text as well as companion to clinical virology references. Author Biography Reeti Khare is the Director of Microbiology at Northwell Health laboratories. Table of Contents PrefaceAcknowledgmentsAbbreviationsAbout the AuthorSection I: Foundations of Clinical Virology1 Introduction to VirusesVirus structure, life cycle, Baltimore classification, figures of DNA and RNA virus classification, transmission, nomenclature2 Laboratory Diagnosis of Viral InfectionsDifferential diagnosis for viral syndromes, specimen collection, comparison of diagnostic techniquesSection II: Viral Pathogens and Clinical Presentation3 Respiratory VirusesInfluenza virus, respiratory syncytial virus, human metapneumonvirus, rhinovirus, coronavirus, mumps virus, diagram of seasonality4 Viruses with Dermatologic ManifestationsHerpes simplex virus, varicella-zoster virus, measles virus, rubella virus, human herpesviruses 6 and 7, molluscum contagiosum, smallpox virus, figure of viral rashes, description and comparison of herpesviruses 1 to -8 5 Gastrointestinal and Fecal-Oral Hepatitis VirusesRotavirus, norovirus, astrovirus, sapovirus, HAV, HEV, diagram of seasonality6 Viruses That Can Cause Multiple SyndromesEnterovirus and parechovirus, adenovirus, parvovirus B19, human bocavirus7 Opportunistic, Transplant-Associated VirusesCytomegalovirus, BK virus, JC virus8 Blood-Borne Hepatitis VirusesHepatitis B, C, and D viruses, and comparison of hepatitis viruses A through E9 Human RetrovirusesHIV, HTLV-1/-210 Oncogenic VirusesHPV, EBV, HHV-811 Zoonotic VirusesRabies virus, Ebola virus, Marburg virus, Lassa virus, Crimean Congo hemorrhagic virus, hantavirus, lymphochoriomeningitis virus, monkeypox virus, herpes B virus, Hendra virus, Nipah virus, comparison of zoonotic viruses12 ArbovirusesMosquitoes, ticks, dengue virus, yellow fever virus, chikungunya virus, West Nile virus, eastern, western and Venezuelan equine encephalitis viruses, Japanese encephalitis virus, Powassan virus, comparison of arboviruses Section III: Diagnostic Assays and Techniques13 Culture- and Tissue-Based Diagnostic TechniquesConventional viral culture and cell lines, viral growth rates, hemagglutination, quantification of plaques, histology/cytology, histologic and cytologic images of virally infected cells14 Diagnostic Techniques Based on Immunological InteractionsKinetics of immune responses, interpreting serologic results, antigen and antibody detection, ELISA and chemiluminescent immunoassay, immunohistochemistry, immunoblots, immunofluorescence, lateral-flow assay, comparison of immunologic assays15 Molecular Techniques: Nucleic Acid AmplificationBasics of nucleic acids, nucleic acid amplification, PCR, RT-PCR, real-time PCR, quantitative PCR, melt curve analysis, viral loads, droplet digital PCR, nested PCR, multiplex PCR, transcription-mediated amplification, controls, contamination16 Molecular Techniques: SequencingSequencing terminology, applications, procedures, platforms (Sanger, NGS, Illumina, SMRT, Ion Torrent), data analysis, comparison of platforms Section IV: Prevention and Management of Viral Infections17 BiosafetyBiosafety levels, select agents, reportable diseases, PPE, techniques, biosafety cabinets, isolation precautions18 VaccinesActive and passive immunity, intravenous immunoglobulin, types of vaccines, delivery, complications, antibody dependent enhancement, table of available viral and other vaccines, diagram of routine vaccination schedule19 AntiviralsAntivirals against herpesviruses, influenza virus, RSV, hepatitis C, other compounds, antiretrovirals and antivirals with broad coverage, mechanisms of actionSection V: The Regulatory Environment for Laboratory Testing20 Regulatory RequirementsClassification of assays by the FDA, test complexity, regulatory agencies, CLIA, inspections, proficiency testing, billing and coding21 Assay Performance and InterpretationValidation/verification, performance characteristics (precision, accuracy, reportable range, reference range), diagnostic, clinical and analytic sensitivity and specificity, prevalence, predictive value, ROC curvesReferencesAnswersIndex Review Reeti Khares Guide to Clinical and Diagnostic Virology uses simple language in an abbreviated format to describe the general characteristics, epidemiology, clinical disease, and diagnostic approaches for all the important viruses of human disease. It has numerous figures and tables that aid in understanding basic concepts in clinical virology. In addition, each chapter ends with a series of review questions so students can self-assess their understanding of the material covered in that chapter. This book is at an introductory level ideal for pre-health students as well as medical, dental, nursing, and physician assistant students who do not have a formal course in microbiology but want a rapid review of clinical virology in preparation for their board examinations. -Peter H. Gilligan, PhD, Professor of Pathology-Laboratory Medicine and Microbiology-Immunology, University of North Carolina School of Medicine Review Text At A Glance The explosion in clinical testing has been especially rapid in virology, where emerging viruses and growing numbers of viral infections are driving advances. The Guide to Clinical and Diagnostic Virology offers a digestible view of the breadth and depth of information related to clinical virology, providing a practical, working knowledge of the wide array of viruses that cause human disease. Introductory chapters cover the basics of clinical virology and laboratory diagnosis of infections, including virus structure, life cycle, transmission, taxonomy, specimen types and handling, and a comparison of assays used for detection. Description This is an abbreviated overview of the field of virology, starting with classification and nomenclature and basic laboratory diagnostic techniques, and finishing with chapters on prevention, management, and regulatory issues. It is a review, complete with tables, illustrations, and end-of-chapter quizzes to improve comprehension. Purpose In the preface, the author acknowledges that the field of clinical and diagnostic virology is rapidly evolving and declares the purpose is to provide a "simple reference for medical and scientific professionals." She achieves this by identifying key concepts in the field of virology and dividing them into chapters organized in an outline format. Combined with simple but effective illustrations and tables, this book is a worthy introduction to a field that can otherwise overwhelm students. Audience The author specifies that this book is designed for a wide range of professionals in medical and laboratory fields. It certainly serves as a well-organized introduction to an otherwise complex field and it can be used as a review or an outline for more in-depth study of the topics. Graduate level students and fellows in microbiology and infectious diseases will need to supplement with books that cover pathophysiology, mechanisms of action, and diagnostic techniques in greater depth. The author has her PhD in virology and gene therapy from Mayo Clinic with a research focus on viruses as vectors and oncolytic agents. She is extensively published and has a clinical microbiology fellowship from Mayo Clinic. Features This book does an excellent job of highlighting concepts that are essential to understand in clinical and diagnostic virology. With well-organized chapters, it breaks down an otherwise complicated field into outlines, making the book easy to read. Key concepts are highlighted in the margins and important terminology is in bold, further enhancing readability. Illustrations and tables are simple, yet well organized and effective. Sections and chapters are demarcated by colors for effective studying, and the multiple-choice questions at the end of each chapter are well-written and designed for maximum comprehension. The references are not terribly complete and further study of topics would be best covered by a comprehensive virology textbook, but this book very effectively meets its objectives. Assessment Either as an introduction to the field of virology for college students or as a review for students in the field of microbiology, infectious diseases, or pathology, this is a well-organized and engaging book. The author carefully and appropriately chose key concepts and achieved an excellent balance of depth and breadth on each topic -- very difficult to do for a review of such a comprehensive subject as virology. I enjoyed reading this book and would recommend it to my internal medicine residents and infectious diseases fellows. Review Questionnaire Range Question Score 1-10 Are the authors objectives met? 10 1-10 Rate the worthiness of those objectives. 10 1-5 Is this written at an appropriate level? 5 1-5 Is there significant duplication? (1=significant, 5=insignificant) 4 1-5 Are there significant omissions? (1=significant, 5=insignificant) 4 1-5 Rate the authority of the authors. 4 1-5 Are there sufficient illustrations? 5 1-5 Rate the pedagogic value of the illustrations. 4 1-5 Rate the print quality of the illustrations. 4 1-5 Are there sufficient references? 5 1-5 Rate the currency of the references. 4 1-5 Rate the pertinence of the references. 5 1-5 Rate the helpfulness of the index. 5 1-5 If important in this specialty, rate the physical appearance of the book 5 1-10 Is this a worthwhile contribution to the field? 8 1-10 If this is a 2nd or later edition, is this new edition needed? N/A -Cynthia Rivera, MD, FACP (Florida International University Health) Review Quote "Reeti Khares Guide to Clinical and Diagnostic Virology uses simple language in an abbreviated format to describe the general characteristics, epidemiology, clinical disease, and diagnostic approaches for all the important viruses of human disease. It has numerous figures and tables that aid in understanding basic concepts in clinical virology. In addition, each chapter ends with a series of review questions so students can self-assess their understanding of the material covered in that chapter. This book is at an introductory level ideal for pre-health students as well as medical, dental, nursing, and physician assistant students who do not have a formal course in microbiology but want a rapid review of clinical virology in preparation for their board examinations." -Peter H. Gilligan, PhD, Professor of Pathology-Laboratory Medicine and Microbiology-Immunology, University of North Carolina School of Medicine Details ISBN1555819915 Publisher American Society For Microbiology Year 2019 ISBN-10 1555819915 ISBN-13 9781555819910 Format Hardcover Imprint American Society for Microbiology Place of Publication Washington DC Country of Publication United States DEWEY 616.9101 Language English Audience Professional and Scholarly Illustrations 4 Illustrations, color AU Release Date 2019-03-01 NZ Release Date 2019-03-01 US Release Date 2019-03-01 UK Release Date 2019-03-01 Pages 460 Publication Date 2019-03-01 Author Reeti Khare Series Asm Books We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! 30 DAY RETURN POLICY No questions asked, 30 day returns! 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