Description: Neuroblastoma Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). mIBG in its Diagnosis and Management Author(s): Sue L. Fielding, Judy S.E. Moyes, Maggie A. Flower, V. Ralph McCready, Ann C. Fullbrook, B.G. Tyrwhitt-Drake Format: Paperback Publisher: Springer London Ltd, United Kingdom Imprint: Springer London Ltd ISBN-13: 9781447116769, 978-1447116769 Synopsis Neuroblastoma is the third most common malignancy of childhood. accounting for 8% of all cancers in patients under 15 years of age. In the majority of cases. by the time neuroblastoma is diagnosed. it has already spread from its site of origin to involve distant sites. Approximately 90% of cases of neuroblastoma can be diagnosed by a combination of techniques including detection of specific tumour markers in the urine. histopathological and immunocytological assessment of involved bone marrow and the 'characteristic' appearances of tumours dem- onstrated by computerised tomography and ultrasonography. However. despite this plethora of techniques. up to. 10% of cases of neuroblastoma are still difficult to diagnose and rely on excisional biopsy of a site of disease. It was against this background that the scintigraphic localisation of neuroblastoma with the radiolabelled guanethidine analogue. mIBG. became available. With mIBG scintigraphy it is now possible to demonstrate the presence of neuro- blastoma (and related tumours) at the primary site. soft tissue sites. in the bone marrow and in cortical bone. in a single investigation. The success of mIBG scintigraphy depends on many factors including the choice of isotope for labelling the mIBG. the equipment used to carry out the procedure. and the manipulation and interpretation of the information obtained. At the Royal Marsden Hospital we have performed over 100 mIBG studies in children. and our advice has frequently been sought by other centres who are. or intend to become.
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Book Title: Neuroblastoma
Number of Pages: 168 Pages
Publication Name: Neuroblastoma: Mibg in Its Diagnosis and Management
Language: English
Publisher: Springer London LTD
Item Height: 280 mm
Subject: Medicine
Publication Year: 2011
Type: Textbook
Item Weight: 457 g
Author: V. Ralph Mccready, Judy S.E. Moyes, Ann C. Fullbrook
Item Width: 210 mm
Format: Paperback
